Asiaticoside
INCI · Asiaticoside · also Centella Asiaticoside
How it works
Asiaticoside is one of the primary triterpenoid saponins found in Centella asiatica (gotu kola), alongside madecassoside and asiatic acid, and it is often considered the most bioactive of the three for wound-healing applications. It is thought to stimulate fibroblast proliferation and type I collagen synthesis, supporting wound healing and tissue remodeling, while also promoting angiogenesis, the formation of new blood vessels, to support tissue repair. It also demonstrates anti-inflammatory activity, helping calm irritated, reactive, or barrier-compromised skin, and has been studied for its role in reducing excessive scar tissue formation.
The evidence
Research on Centella asiatica extracts, including isolated asiaticoside, supports its role in promoting wound healing and reducing hypertrophic scar formation, with studies examining its effects on collagen synthesis, tensile strength of healing tissue, and angiogenesis in both animal and cell-culture models. Much of the cosmetic formulation evidence draws on the broader Centella asiatica research base, since asiaticoside is one of its key active constituents rather than always studied in complete isolation from the whole-plant extract.
Suitability
- Well suited to sensitive, redness-prone, and post-procedure skin recovering from in-office treatments such as microneedling or chemical peels.
- Commonly used in scar-support and barrier-repair formulations aimed at healing support.
- Generally well tolerated across skin types, including acne-prone skin, due to its calming, anti-inflammatory profile.
Concentration
- Cosmetic formulations typically use asiaticoside at low concentrations, often under 1%.
- Frequently formulated alongside other Centella-derived compounds, such as madecassoside and asiatic acid, rather than as a sole isolated active.
- Results for scar appearance and redness are typically assessed over weeks to months of consistent use.
Conflicts & combinations
- No significant known conflicts with common actives.
- Pairs well with other soothing and barrier ingredients like panthenol and allantoin.
- Frequently combined with madecassoside and full Centella asiatica extract for layered soothing and tissue-repair benefits.
- Considered compatible with most exfoliating acids and retinoids as a calming counterbalance in a routine.
- redness
- uneven texture
- anti aging
- Effective from
- 0.1%
- Max safe
- 1%
What is asiaticoside used for in skincare?
It is used to support wound healing, calm irritated skin, and promote collagen synthesis, often in scar-care and barrier-repair products.
Is asiaticoside the same as centella asiatica?
Asiaticoside is one of the key active compounds found within Centella asiatica extract, alongside madecassoside and asiatic acid, rather than being a separate plant source.
Is asiaticoside good for sensitive skin?
Yes, it is generally well tolerated and valued for its calming, anti-inflammatory properties on reactive or redness-prone skin.
Can asiaticoside help with scars?
Research suggests it can support collagen synthesis and tissue repair, which is why it appears in many scar-focused skincare formulations.
Is asiaticoside safe during pregnancy?
Specific pregnancy safety data is limited, so it is classified as unknown and discussing use with a healthcare provider is recommended.
- PubMedPMID 21076566 ↗