Phenoxyethanol
INCI · Phenoxyethanol
How it works
Phenoxyethanol is a synthetic glycol ether, CAS 122-99-6, used as a broad-spectrum cosmetic preservative. It disrupts microbial cell membranes and inhibits enzyme activity in bacteria, yeast and mould, which prevents product spoilage and protects the user from contamination introduced during normal use — fingers in a jar, a pump left open, a bottle in a warm bathroom. It became the default in modern formulation largely as a lower-sensitisation alternative to parabens and to formaldehyde-releasing preservatives. It does occur naturally in trace amounts in green tea and chicory, but cosmetic-grade material is synthesised rather than extracted, and "naturally occurring" is not a meaningful selling point here.
The evidence
It is one of the most extensively safety-reviewed preservatives in cosmetics, with a long documented history of safe use at approved concentrations in industry and regulatory toxicology literature. This is a preservative, so the standard it must meet is safety and antimicrobial performance, not skin efficacy — there is no anti-ageing or barrier claim attached to it, nor should there be.
Suitability
Generally well tolerated at approved concentrations. Rare contact sensitisation has been documented in a small subset of individuals. France's ANSM has issued a precautionary advisory against use on the diaper area of infants below specific age thresholds — a narrow, population-specific caution rather than a broad restriction, and one worth reading in that context.
Concentration
The EU Cosmetics Regulation permits a maximum of 1% in finished cosmetic products under Annex V; most commercial formulations use 0.3%–1%. The US FDA permits it without an equivalent hard cap, but 1% has become the de facto global ceiling because EU rules shape formulation practice worldwide.
Conflicts & combinations
Very commonly paired with ethylhexylglycerin, a preservative booster that disrupts microbial membranes and lets a lower total preservative load do the same job. No conflicts with treatment actives are described.
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Is phenoxyethanol safe?
It is one of the most extensively safety-reviewed cosmetic preservatives, with a long documented record of safe use at approved concentrations.
How much phenoxyethanol is allowed?
The EU Cosmetics Regulation caps it at 1% in finished products under Annex V; most formulations use 0.3%–1%.
Why is there a warning about babies?
France's ANSM issued a precautionary advisory against use on the diaper area of infants below specific age thresholds — a narrow, population-specific caution, not a general restriction.
Is phenoxyethanol natural?
It occurs in trace amounts in green tea and chicory, but cosmetic-grade material is synthesised, not extracted.
Why is it used instead of parabens?
It was adopted widely as a lower-sensitisation alternative to parabens and to formaldehyde-releasing preservatives.