By concern

Best ingredients for signs of aging

Fine lines and loss of firmness track with collagen decline and sun damage. These ingredients have the best-supported evidence for visible signs of aging — from retinoids to antioxidants.

112 ingredientsListed with our own conservative safety grade — an evidence roundup, not a medical efficacy ranking.

Ranked ingredients for this concern

  1. Anti-aging

    Adenosine

    Smooths fine lines and calms skin by supporting cellular energy and repair processes.

    Read the guide →
  2. Barrier

    Argan Oil

    Argania Spinosa Kernel Oil

    Softens skin and supplies antioxidants that support elasticity and barrier function.

    Read the guide →
  3. Antioxidant

    Ascorbyl Glucoside

    Delivers a stable, water-soluble form of vitamin C that converts to active ascorbic acid in skin.

    Read the guide →
  4. Soothing

    Asiaticoside

    A triterpenoid saponin isolated from Centella asiatica, studied for wound healing and collagen support.

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  5. Antioxidant

    Astaxanthin

    A carotenoid antioxidant derived from microalgae, studied for reducing oxidative damage and supporting skin elasticity.

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  6. Barrier

    Bifida Ferment Lysate

    Strengthens the skin barrier and calms sensitivity using fermented probiotic filtrate.

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  7. Antioxidant

    Caffeine

    A stimulant antioxidant that constricts blood vessels and helps reduce puffiness, redness, and photoaging markers.

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  8. Barrier

    Ceramides

    Ceramide NP

    Replenishes the lipids that hold the skin barrier together, locking in moisture and blocking irritants.

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  9. Barrier

    Cholesterol

    A key lipid that, alongside ceramides and fatty acids, rebuilds and reinforces the skin barrier.

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  10. Antioxidant

    Coenzyme Q10

    Ubiquinone

    A fat-soluble antioxidant the body makes itself, which declines with age and is used topically to reduce oxidative damage.

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  11. Humectant

    Collagen

    Hydrolyzed Collagen

    Hydrolyzed collagen peptides that hydrate the surface and support the skin's own structural proteins.

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  12. Antioxidant

    CoQ10

    Ubiquinone

    A mitochondrial antioxidant that neutralizes free radicals and supports collagen-producing cells.

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  13. Barrier

    Ectoin

    Protects skin cells from environmental stress and locks in moisture at a cellular level.

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  14. Antioxidant

    EGCG (Green Tea)

    Camellia Sinensis Leaf Extract

    The main polyphenol in green tea, delivering strong antioxidant and anti-inflammatory action.

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  15. Antioxidant

    Ferulic Acid

    Neutralizes free radicals and dramatically boosts the stability and potency of vitamin C.

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  16. Brightening

    Galactomyces Ferment

    Galactomyces Ferment Filtrate

    A yeast fermentation filtrate rich in vitamins, minerals, and organic acids, used to improve tone, texture, and radiance.

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  17. Anti-aging

    Ginseng

    Panax Ginseng Root Extract

    Supplies ginsenosides that fight oxidative stress and support firmer, more radiant-looking skin.

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  18. Antioxidant

    Ginseng Extract

    Panax Ginseng Root Extract

    A root extract whose ginsenosides give antioxidant and anti-inflammatory activity, and a long history in Korean formulation.

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  19. Brightening

    Glutathione

    A tripeptide antioxidant studied for lightening overall skin tone and buffering oxidative stress.

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  20. Barrier

    Grapeseed Oil

    Vitis Vinifera Seed Oil

    Provides lightweight moisture and antioxidant polyphenols that help protect the skin barrier.

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  21. Humectant

    Hyaluronic Acid

    Sodium Hyaluronate

    Draws water into the skin's surface for an immediate, visible plumping effect.

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  22. Antioxidant

    Magnesium Ascorbyl Phosphate

    Provides a stable, water-soluble vitamin C derivative that supports brightening and antioxidant defense.

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  23. Barrier

    Marula Oil

    Sclerocarya Birrea Seed Oil

    Provides fast-absorbing emollient hydration with a high antioxidant fatty acid content.

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  24. Anti-aging

    Palmitoyl Pentapeptide-4

    A signal peptide, sold as Matrixyl, that mimics a collagen fragment and prompts fibroblasts to build more matrix.

    Read the guide →
  25. Antioxidant

    Phloretin

    A polyphenol from apple that scavenges free radicals and gets through the stratum corneum unusually well for its class. It is almost always sold inside a fixed combination with vitamin C and ferulic acid.

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  26. Anti-aging

    Pro-Xylane

    Hydroxypropyl Tetrahydropyrantriol

    A small molecule made from the plant sugar xylose, formulated to support glycosaminoglycan synthesis in the layer that joins epidermis to dermis.

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  27. Antioxidant

    Resveratrol

    A potent plant polyphenol that neutralizes free radicals and supports collagen-protective antioxidant defense.

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  28. Barrier

    Rosehip Oil

    Rosa Canina Fruit Oil

    Nourishes dry skin and supplies antioxidants and essential fatty acids that support the barrier.

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  29. Antioxidant

    Sea Buckthorn

    Hippophae Rhamnoides Oil

    A carotenoid- and fatty-acid-rich oil that supports antioxidant defense and skin barrier repair.

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  30. Barrier

    Sea Buckthorn Oil

    Hippophae Rhamnoides Oil

    A carotenoid-rich plant oil that comes in two very different forms — fruit and seed — with different fatty acids and very different colour.

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  31. Antioxidant

    Sodium Ascorbyl Phosphate

    Delivers a stable vitamin C derivative with additional evidence supporting anti-acne and antioxidant activity.

    Read the guide →
  32. Barrier

    Squalane

    A stable, lightweight emollient that mimics skin's natural sebum to soften and protect the barrier without greasiness.

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  33. Antioxidant

    Sulforaphane

    Brassica Oleracea Italica (Broccoli) Sprout Extract

    An indirect antioxidant from broccoli sprouts that switches on the skin’s own protective enzymes rather than being consumed itself.

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  34. Antioxidant

    THD Ascorbate

    Tetrahexyldecyl Ascorbate

    Offers a highly stable, oil-soluble vitamin C form that penetrates the skin barrier efficiently.

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  35. Antioxidant

    Vitamin C

    Ascorbic Acid

    Neutralizes free radicals, brightens dull skin, and supports collagen production.

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  36. Antioxidant

    Alpha Lipoic Acid

    Thioctic Acid

    A potent antioxidant that neutralizes free radicals and regenerates other antioxidants like vitamin C and E.

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  37. Anti-aging

    Argireline

    Acetyl Hexapeptide-8

    A synthetic hexapeptide marketed as a topical alternative to neurotoxin injections for expression lines.

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  38. Anti-aging

    Bakuchiol

    Delivers retinol-like smoothing and firming without the flaking or sun sensitivity.

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  39. Antioxidant

    Melatonin

    A hormone that is also a potent antioxidant, used topically at night to reduce oxidative stress rather than to affect sleep.

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  40. Brightening

    Noni

    Morinda Citrifolia Fruit Extract

    Delivers antioxidant polyphenols that help fade dullness and support a more even tone.

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  41. Anti-aging

    Oligopeptides

    Oligopeptide-1

    Short chains of amino acids that signal skin cells to behave younger — more collagen, better repair.

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  42. Anti-aging

    Palmitoyl Tripeptide-1

    A fatty-acid-conjugated peptide fragment of collagen, studied for stimulating collagen synthesis in aging skin.

    Read the guide →
  43. Anti-aging

    Peptides (Matrixyl)

    Palmitoyl Pentapeptide-4

    Signals skin to produce more collagen, gradually softening fine lines.

    Read the guide →
  44. Antioxidant

    Vitamin E (Tocopherol)

    Tocopherol

    A fat-soluble antioxidant that protects skin lipids from oxidative damage and works best paired with vitamin C.

    Read the guide →
  45. Sunscreen

    Zinc Oxide (SPF)

    Zinc Oxide

    Physically reflects and scatters UVA and UVB rays, protecting skin from sun damage and photoaging.

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  46. Anti-aging

    Copper Peptides (GHK-Cu)

    Copper Tripeptide-1

    A copper-binding tripeptide studied for stimulating collagen production and supporting wound healing and skin firmness.

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  47. Anti-aging

    EGF (Epidermal Growth Factor)

    sh-Oligopeptide-1

    A signaling protein that tells skin cells to proliferate and repair, supporting firmer, more resilient skin over time.

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  48. Anti-aging

    Granactive Retinoid

    Hydroxypinacolone Retinoate

    Binds directly to retinoid receptors without requiring conversion, offering retinoid effects with less irritation.

    Read the guide →
  49. Barrier

    Royal Jelly

    Royal Jelly Extract

    A bee secretion containing 10-HDA, proteins and vitamins, with a documented record of serious allergic reactions.

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  50. Antioxidant

    Fullerene

    Fullerenes

    A carbon-cage nanomaterial studied as a potent free-radical scavenger for anti-aging formulations.

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  51. Anti-aging

    Retinal (Retinaldehyde)

    Retinal

    A fast-acting retinoid, one conversion step from retinoic acid, that speeds cell turnover and rebuilds collagen.

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  52. Anti-aging

    Retinyl Palmitate

    Provides the mildest, slowest-converting retinoid ester, offering gentle anti-aging support.

    Read the guide →
  53. Anti-aging

    Retinol

    Speeds up cell turnover and stimulates collagen, smoothing texture and softening fine lines over months.

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  54. Brightening

    3-O-Ethyl Ascorbic Acid

    An ethyl-ether derivative of vitamin C, engineered to stay stable across a normal formulation pH while keeping a structure close to the parent molecule.

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  55. Anti-aging

    Acetyl Octapeptide-3

    A synthetic eight-amino-acid peptide sold as a topical route to softening expression lines, and closely related in concept to acetyl hexapeptide-8. It is meant to interfere with the signalling that drives repeated muscle contraction.

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  56. Anti-aging

    Acetyl Tetrapeptide-5

    A peptide used mainly in eye products to support the look of firmer, less puffy skin and reduce the appearance of under-eye shadows. It is positioned for the delicate eye area.

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  57. Antioxidant

    Ascorbyl Palmitate

    An oil-soluble vitamin C ester used for antioxidant protection and to help stabilize formulas against oxidation. Its lipid solubility makes it easy to include in anhydrous and oil-based products.

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  58. Antioxidant

    Beta-Carotene

    A carotenoid antioxidant and precursor to vitamin A that helps protect skin from oxidative stress and conditions the surface. It also lends a natural orange tint to formulas.

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  59. Antioxidant

    BHT

    A synthetic antioxidant that protects the oils and fragrance in a formula from going rancid. It is used at very small levels and its target is the product in the bottle, not the skin the product goes on.

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  60. Antioxidant

    Bilberry Fruit Extract

    Vaccinium Myrtillus Fruit Extract

    An extract of the European blueberry, rich in the deep-purple anthocyanins that behave as antioxidants in laboratory testing. It is also a mild source of plant acids, which is where the marketing habit of calling it a 'natural AHA' comes from.

    Read the guide →
  61. Barrier

    Black Cumin Seed Oil

    Nigella Sativa Seed Oil

    A traditional plant oil rich in fatty acids and thymoquinone that conditions skin and is used to calm the look of blemished, reactive skin. It has antioxidant properties.

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  62. Barrier

    Camellia Oil

    Camellia Japonica Seed Oil

    A silky plant oil, traditional in Japanese skincare, that is high in oleic acid and antioxidants and absorbs relatively quickly to soften skin. It leaves a light, conditioned finish.

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  63. Antioxidant

    Carnosine

    A dipeptide antioxidant that helps protect skin proteins from glycation and oxidative stress, supporting the look of firmer, healthier skin. It is used in anti-aging antioxidant blends.

    Read the guide →
  64. Antioxidant

    Curcumin (Turmeric)

    Curcuma Longa Root Extract

    The main antioxidant compound of turmeric, used to help defend skin against oxidative stress and calm the look of irritation. It has a long history in traditional care.

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  65. Sunscreen

    Diethylhexyl Butamido Triazone

    A large, oil-soluble UVB filter sold under names including Iscotrizinol and Uvasorb HEB. Its molecular size keeps it on the skin surface, and it is photostable enough to be used as a partner that helps hold less stable filters together.

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  66. Anti-aging

    Dipeptide Diaminobutyroyl Benzylamide Diacetate

    A synthetic peptide marketed to soften the look of expression lines by dampening muscle-contraction signaling at the skin surface, sometimes called a topical 'snake-venom-inspired' peptide. Its effect is far milder than injectable treatments.

    Read the guide →
  67. Antioxidant

    Edelweiss Extract

    Leontopodium Alpinum Extract

    An alpine-plant extract rich in antioxidant compounds that helps protect skin from environmental stress and supports a calmer surface. It is popular in protective and anti-aging formulas.

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  68. Brightening

    Ellagic Acid

    A polyphenol antioxidant found in berries and pomegranate that helps protect skin from oxidative stress and supports a more even tone. It is used for both antioxidant and brightening purposes.

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  69. Antioxidant

    Epigallocatechin Gallate

    The main catechin in green tea, isolated rather than left in a whole leaf extract. It is one of the most studied plant antioxidants in the laboratory, where it also shows calming activity, and appears in serums framed around pollution and redness.

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  70. Antioxidant

    Ergothioneine

    A sulphur-containing amino acid derivative concentrated in certain mushrooms, which the body takes up through a dedicated transporter. In formulas it acts as a stable antioxidant, often paired with vitamin C or E to spread the workload.

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  71. Soothing

    Ginger Extract

    Zingiber Officinale Root Extract

    A root extract with antioxidant compounds used to help protect and comfort skin and support a healthy-looking, refreshed appearance. It has warming, invigorating character.

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  72. Antioxidant

    Ginkgo Biloba Extract

    Ginkgo Biloba Leaf Extract

    A leaf extract rich in flavonoid antioxidants used to protect skin from oxidative stress and support a calmer, more comfortable surface. It is a common botanical in protective formulas.

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  73. Soothing

    Helichrysum Extract

    Helichrysum Italicum Extract

    A botanical extract, also known as immortelle, used to soothe and support the look of stressed skin, with antioxidant properties. It is popular in calming and recovery formulas.

    Read the guide →
  74. Brightening

    Hexylresorcinol

    A resorcinol-derived active that helps fade the look of dark spots and even tone, with additional antioxidant activity. It is often positioned as a gentler alternative to hydroquinone.

    Read the guide →
  75. Sunscreen

    Homosalate

    A common organic UVB filter that absorbs ultraviolet-B radiation and helps dissolve other sunscreen actives in a formula. It gives lightweight, cosmetically elegant textures.

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  76. Antioxidant

    Hydroxyacetophenone

    A multifunctional ingredient used as an antioxidant and soothing agent that also helps stabilize formulas and support preservation. It is valued for calming and protective roles.

    Read the guide →
  77. Antioxidant

    Idebenone

    A synthetic antioxidant related to coenzyme Q10 that helps neutralize free radicals and protect skin from oxidative and environmental stress. It is used in anti-aging and protective formulas.

    Read the guide →
  78. Sunscreen

    Iron Oxides

    The red, yellow and black mineral pigments that give tinted sunscreens, foundations and BB creams their colour. Because they are opaque across the visible range they also block visible light, which UV filters on their own do not.

    Read the guide →
  79. Exfoliant

    Lactobionic Acid

    A polyhydroxy acid formed by oxidising lactose — a large molecule that exfoliates slowly and gently, with documented antioxidant and metal-chelating activity alongside.

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  80. Humectant

    Laminaria (Kelp) Extract

    Laminaria Digitata Extract

    A brown-seaweed extract used as a mineral-rich humectant and skin-conditioning agent that helps hydrate and soften the surface. It also supplies antioxidant polysaccharides.

    Read the guide →
  81. Antioxidant

    Lycopene

    A carotenoid antioxidant, responsible for the red color of tomatoes, used to help defend skin against free-radical and light-induced stress. It is a potent lipid-soluble antioxidant.

    Read the guide →
  82. Sunscreen

    Mexoryl SX

    Terephthalylidene Dicamphor Sulfonic Acid

    A photostable organic UVA filter developed for strong short-UVA protection, often combined with other filters for broad-spectrum defense. It is a signature filter of certain European sunscreen lines.

    Read the guide →
  83. Sunscreen

    Mexoryl XL

    Drometrizole Trisiloxane

    A photostable organic filter that absorbs across both UVA and UVB, valued for helping deliver broad-spectrum protection in stable formulas. It is oil-soluble and complements water-soluble filters.

    Read the guide →
  84. Brightening

    Mulberry Extract

    Morus Alba Root Extract

    A botanical extract used to help even skin tone and reduce the look of dark spots by moderating pigment-enzyme activity, alongside antioxidant benefits. It is a common natural brightening ingredient.

    Read the guide →
  85. Sunscreen

    Octinoxate

    Ethylhexyl Methoxycinnamate

    One of the most common organic (chemical) UVB filters, which absorbs ultraviolet-B radiation to help prevent sunburn. It is oil-soluble and widely used in sunscreens worldwide.

    Read the guide →
  86. Sunscreen

    Octisalate

    Ethylhexyl Salicylate

    A gentle organic UVB filter that absorbs ultraviolet-B and also helps solubilize and stabilize other filters. It is valued for its mildness and water resistance.

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  87. Sunscreen

    Octocrylene

    An organic UV filter that absorbs UVB and short UVA rays and is often added to stabilize other filters such as avobenzone. It also improves the water resistance of sunscreens.

    Read the guide →
  88. Sunscreen

    Oxybenzone

    Benzophenone-3

    An organic filter that absorbs both UVB and some UVA radiation and has historically been used to broaden sunscreen protection. It is one of the more studied and debated chemical filters.

    Read the guide →
  89. Anti-aging

    Palmitoyl Hexapeptide-12

    A conditioning signal peptide used in anti-aging formulas to support the look of smoother, firmer skin. It is often combined with other peptides in blends.

    Read the guide →
  90. Anti-aging

    Palmitoyl Tetrapeptide-7

    A synthetic signal peptide anchored to palmitic acid, intended to inhibit interleukin-6, an inflammatory cytokine implicated in inflammaging and collagen breakdown.

    Read the guide →
  91. Anti-aging

    Palmitoyl Tripeptide-5

    A short peptide with a fatty acid tail attached so it mixes into the skin's lipids more readily. Suppliers describe it as a signal peptide meant to nudge the pathways involved in collagen production, and it is usually blended with other peptides.

    Read the guide →
  92. Anti-aging

    PDRN (Salmon DNA)

    Sodium DNA

    A polydeoxyribonucleotide derived from salmon DNA, used in serums for tissue regeneration and skin repair support.

    Read the guide →
  93. Sunscreen

    Phenylbenzimidazole Sulfonic Acid

    A water-soluble UVB filter, unusual in a category dominated by oil-soluble molecules. Being water-soluble lets it sit in the water phase, which is how some sunscreens achieve a very light, non-greasy feel.

    Read the guide →
  94. Brightening

    Phenylethyl Resorcinol

    A potent resorcinol-based cosmetic brightener used to reduce the appearance of dark spots and even tone, with antioxidant activity. It is effective at low concentrations.

    Read the guide →
  95. Antioxidant

    Pine Bark Extract

    Pinus Pinaster Bark Extract

    A maritime-pine bark extract rich in proanthocyanidin antioxidants used to protect skin against free-radical and environmental stress. It is a popular potent botanical antioxidant.

    Read the guide →
  96. Sunscreen

    Polysilicone-15

    An organic UV filter attached to a silicone backbone, which makes the molecule large and keeps it sitting on the skin surface rather than being absorbed. It absorbs in the UVB range and is approved for sunscreen use in the EU and several other regions, though not in the United States.

    Read the guide →
  97. Antioxidant

    Pomegranate Extract

    Punica Granatum Extract

    A fruit extract high in polyphenol antioxidants, including ellagic acid, that helps protect skin against environmental stress. It is valued for antioxidant and conditioning support.

    Read the guide →
  98. Barrier

    Pomegranate Seed Oil

    Punica Granatum Seed Oil

    A plant oil distinctive for its punicic-acid content, an omega-5 fatty acid, that conditions skin and provides antioxidant support. It helps replenish the barrier.

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  99. Barrier

    Prickly Pear Seed Oil

    Opuntia Ficus-Indica Seed Oil

    A lightweight, linoleic-acid-rich plant oil high in vitamin E that conditions skin and provides antioxidant support with a fast-absorbing feel. It is prized in luxury facial oils.

    Read the guide →
  100. Antioxidant

    Quercetin

    A plant flavonoid antioxidant that helps neutralize free radicals and calm the look of stressed skin. It is found widely in fruits and vegetables.

    Read the guide →
  101. Anti-aging

    Retinyl Propionate

    An ester form of vitamin A that converts in the skin to support renewal and the look of smoother, firmer skin, offering a gentler retinoid option. It is milder than retinol for sensitive users.

    Read the guide →
  102. Anti-aging

    Retinyl Retinoate

    A hybrid vitamin A derivative combining retinol and retinoic-acid fragments, designed to support skin renewal and the look of firmness while aiming for better stability than plain retinol. It is a next-generation cosmetic retinoid.

    Read the guide →
  103. Antioxidant

    Rosemary Extract

    Rosmarinus Officinalis Leaf Extract

    A botanical extract rich in antioxidant polyphenols that helps defend skin against oxidative stress and is also used to stabilize oils in formulas. It has mild soothing character.

    Read the guide →
  104. Barrier

    Sesame Oil

    Sesamum Indicum Seed Oil

    A traditional emollient plant oil, prominent in Ayurvedic body care, that softens skin and offers antioxidant support from natural lignans. It has a medium-weight, conditioning feel.

    Read the guide →
  105. Antioxidant

    Superoxide Dismutase

    An antioxidant enzyme that helps neutralize superoxide free radicals, supporting the skin's defenses against oxidative stress. It is used for protective and soothing purposes.

    Read the guide →
  106. Sunscreen

    Tinosorb M

    Methylene Bis-Benzotriazolyl Tetramethylbutylphenol

    A modern broad-spectrum UV filter that both absorbs and scatters UVA and UVB rays, acting partly like a mineral and partly like an organic filter. It is highly photostable but not approved in all markets.

    Read the guide →
  107. Antioxidant

    Tocopheryl Acetate

    A stable ester form of vitamin E that conditions skin and provides antioxidant support once converted in the skin. Its stability makes it a very common addition to moisturizers and sunscreens.

    Read the guide →
  108. Antioxidant

    Tocotrienols

    The second branch of the vitamin E family, sitting alongside the far more familiar tocopherols and usually extracted from annatto, palm or rice bran. Their shorter, unsaturated tail moves more freely through lipid layers than tocopherol does.

    Read the guide →
  109. Humectant

    Trehalose

    A naturally occurring sugar that acts as a humectant and helps protect cell structures against dehydration stress. It supports moisture retention and formula stability.

    Read the guide →
  110. Sunscreen

    Uvinul A Plus

    Diethylamino Hydroxybenzoyl Hexyl Benzoate

    A photostable organic UVA filter that absorbs long-wave ultraviolet-A radiation, helping protect against the deeper, aging effects of sun exposure. It is often paired with UVB filters for broad-spectrum cover.

    Read the guide →
  111. Sunscreen

    Uvinul T 150

    Ethylhexyl Triazone

    A highly efficient, photostable organic UVB filter that provides strong ultraviolet-B absorption at low concentrations. It is prized for its stability and elegant feel.

    Read the guide →
  112. Barrier

    Wheat Germ Oil

    Triticum Vulgare Germ Oil

    A rich plant oil that is one of the highest natural sources of vitamin E, used to nourish dry skin and add antioxidant protection to formulas. It also helps stabilize other oils.

    Read the guide →
The terms behind this concern

Educational, not medical advice. Skin is individual; patch-test new actives and introduce them one at a time.

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RRevelika

A science-forward beauty ingredient encyclopedia. Every entry is written from published research and graded conservatively before it publishes.

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